Asic1 and asic3 contribute to acidity-induced emt of pancreatic cancer through activating ca2+/rhoa pathway

HIGHLIGHTS

• who: Shuai Zhu from the DepartmentHuazhong University of Science and Technology, Wuhan, China have published the Article: ASIC1 and ASIC3 contribute to acidity-induced EMT of pancreatic cancer through activating Ca2+/RhoA pathway, in the Journal: (JOURNAL)
• what: Given that ASIC1 and ASIC3 are the most susceptible to acidic pHe and function as acidic pH sensors the authors investigate whether ASIC1 and ASIC3 are expressed in pancreatic cancer and contribute to acidity-induced EMT of pancreatic cancer. The study elaborates an integrated signaling pathway to account for the effect of acidic microenvironment on invasion and . . .
  

   

  

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