Asp-170 is crucial for the redox properties of vanillyl-alcohol oxidase*

HIGHLIGHTS

• who: Robert H. H. van den Heuvel from the (UNIVERSITY) have published the Article: Asp-170 Is Crucial for the Redox Properties of Vanillyl-alcohol Oxidase*, in the Journal: (JOURNAL) of February/24,/2000
• what: The studies show that covalent flavinylation of VAO is strongly dependent on the identity of residue 170, which is located more than 8 Å from the target residue of flavinylation, His-422. On the basis of these observations, the authors propose that the introduction of Glu-170 changes the electrostatic interactions between the side chain of residue 170 and flavin N5 . . .
  

   

  

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