Asparagine protects pericentral hepatocytes during acute liver injury 2 yu sun , hadrien demagny , adrien faure , francesca pontanari , antoine jalil , 3

HIGHLIGHTS

• who: Sun Yu from the Lausanne, SwitzerlandBiochemistry, Medical University of Graz, Graz, Austria have published the paper: Asparagine protects pericentral hepatocytes during acute liver injury 2 Yu Sun , Hadrien Demagny , Adrien Faure , Francesca Pontanari , Antoine Jalil , 3, in the Journal: (JOURNAL)
• what: The authors demonstrate that a pericentral enzyme, asparagine synthetase (ASNS), colocalizes with GLUL and converts its main product, glutamine, into asparagine. The authors show that during acute liver injury, pericentrally expressed ASNS is highly induced through the enhanced recruitment of the nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) to its promoter . . .
  

   

  

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