Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition

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  • who: Ziyu Wu et al. from the Memorial Hospital and Tianjin Institute of Endocrinology, Tianjin Medical, Tianjin, ChinaEditor: Aldrin VGomes, University of California have published the article: Aspirin mediates protection from diabetic kidney disease by inducing ferroptosis inhibition, in the Journal: PLOS ONE of December/21,/2021
  • what: The research shows that inhibiting ferroptosis has renoprotective properties by downregulating COX2 signaling in PTECs, which illustrates the mechanism of aspirin-mediated renoprotection in DKD. Understandably, this study has demonstrated that COX2 gene disruption can block such depletion of GSH (Fig 5H). The study showed that the . . .

     

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