Aspscr1::tfe3 orchestrates the angiogenic program of alveolar soft part sarcoma

HIGHLIGHTS

  • who: Miwa Tanaka from the (UNIVERSITY) have published the research work: ASPSCR1::TFE3 orchestrates the angiogenic program of alveolar soft part sarcoma, in the Journal: (JOURNAL)
  • what: The study demonstrated that angiogenic promotion occurs at the early stage of tumor growth in_vivo (Fig 1f, Supplementary Fig 1e), indicating that this mechanism is essential for the ASPS development. This study shows the essential role of the ASPSCR1::TFE3 driven pathways in tumor development and angiogenesis.
  • how: The authors evaluated the importance of the ASPSCR1TFE3 and Rab27a/Sytl2 axis using an angiogenesis model. The data . . .

     

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