Assembly and activity of the wash molecular machine: distinctive features at the crossroads of the actin and microtubule cytoskeletons

HIGHLIGHTS

  • who: Alexis M. Gautreau from the Laboratoire de Biologie Structurale de la Cellule, CNRS, Ecole Polytechnique, IP Paris, Palaiseau, France, School Sichuan University, China have published the Article: Assembly and Activity of the WASH Molecular Machine: Distinctive Features at the Crossroads of the Actin and Microtubule Cytoskeletons, in the Journal: (JOURNAL)

SUMMARY

    A detailed map of subunit interactions was derived from in_vitro reconstitutions first and then crystallography (Gautreau et_al, 2004; Innocenti et_al, 2004; Chen et_al, 2010). The native and properly reconstituted WAVE complexes are inactive NPFs, because their WCA motif is masked (Derivery . . .

     

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