Assessing positive and negative valence systems to refine animal models of bipolar disorders: the example of gbr 12909-induced manic phenotype

HIGHLIGHTS

• who: Mathilde Bigot from the Institut have published the paper: Assessing positive and negative valence systems to refine animal models of bipolar disorders: the example of GBR 12909-induced manic phenotype, in the Journal: Scientific Reports Scientific Reports
• how: The results showed that injecting GBR every 2 days generates a robust and stable hyperlocomotion distinctive of mania models. The pairs of odorants used in the experiments were carvone+ or 1-butanol vs their respective solvants.
• future: The olfactory stimulus used was extremely uncontrolled and further experiments are necessary to clarify these discrepancies | Vol . . .
  

   

  

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