Assessment of neurotoxic effects of oxycodone and naloxone in sh-sy5y cell line

HIGHLIGHTS

  • who: Luu00edza Siqueira Lima et al. from the Instituto Pesquisa Pelu00e9 Pequeno Pru00edncipe, Curitiba, Brazil, Universidade Federal do have published the research: Assessment of Neurotoxic Effects of Oxycodone and Naloxone in SH-SY5Y Cell Line, in the Journal: (JOURNAL)
  • what: We can observe that, in addition to the chronic toxicity caused by using opioids, 24 h of exposure to naloxone or oxycodone was also harmful, causing toxic effects to the cells, such as inhibition of enzymes of the antioxidant system and DNA damage without altering cell viability.
  • how: Accelrys discovery studio visualizer was . . .

     

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