HIGHLIGHTS
SUMMARY
Some cohort studies have shown that BC patients treated with RT had a higher risk of morbidity and mortality of cardiac arrhythmia than BC patients not treated with RT. There are distinct etiologies for different types of radiotherapy-associated cardiotoxicity, and the dose-response relationship previously observed between the mean heart dose and the coronary complications cannot be directly applied to arrhythmias. Each patient`s RT was planned such that the dose distribution was optimized and normalized to the International Commission on Radiation Units and Measurements (ICRU) reference point of the breast and to . . .
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