Association between dosing of spironolactone and outcomes in heart failure with preserved ejection fraction patients combined with chronic kidney disease——balance of ef cacy and risk

HIGHLIGHTS

  • who: January and colleagues from the University of California, Los Angeles, United States have published the research work: Association between dosing of spironolactone and outcomes in heart failure with preserved ejection fraction patients combined with chronic kidney disease------Balance of ef cacy and risk, in the Journal: (JOURNAL) of 31/Dec/2019
  • what: The authors aimed to deduce an efficacy-risk-balanced dose through a direct comparison of different dose categories in patients with HFpEF and CKD.
  • how: The authors assessed the association of different eGFR categories and outcomes using the unadjusted Cox . . .

     

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