Association between papillary thyroid cancer and xrcc6 gene polymorphisms in the turkish population

HIGHLIGHTS

  • What: The aim of this study was to investigate whether three different SNPs in the XRCC6 gene promoter region have any contribution to the development of PTC. Contrary to the current study, the UKB and FinnGen databases showed no significant relationship between the rs2267437 polymorphism and PTC (p > 5 × 10-8). In the present study, when the clinical features and genotypes were compared, no statistically significant difference was observed between the groups, but multifocality was found more frequently in patients with the rs2267437 polymorphism and GG and CG+GG genotypes. Different than these studies, the results of . . .

     

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