Association between pazopanib exposure and safety in japanese patients with renal cell carcinoma or soft tissue sarcoma

HIGHLIGHTS

• who: Takeshi Aoyama from the DepartmentShowa University Japan have published the Article: Association between pazopanib exposure and safety in Japanese patients with renal cell carcinoma or soft tissue sarcoma, in the Journal: Scientific Reports Scientific Reports
• what: Twelve patients were excluded for the following reasons: disease progressed before blood sampling (n=5); blood sample not collected (n=6); and agreed to withdraw (n=1). The primary reason for discontinuation was hepatotoxicity (5/14, 35.7%), and nausea or vomiting (1/14, 7.1%). This study investigated the pazopanib plasma trough concentrations in Japanese patients with . . .
  

   

  

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