Association of bdnf gene missense polymorphism rs6265 (val66met) with three quantitative traits, namely, intelligence quotient, body mass index, and blood pressure: a genetic association analysis from north india

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SUMMARY

    BDNF Val66Met polymorphism. The loss of one copy of the BDNF gene in humans is also found to be linked with hyperphagia, severe obesity, reduced cognitive performance, and additionally, poorer locomotor activity. The work indicates that individuals with Met/Met homozygosity have belowaverage verbal IQ (VCI) or higher verbal recall errors, but Val/Val and Val/Met have average values for the same, supported by the fact that there is a decrease in gray matter volume of the hippocampus in BDNF Met allele carriers compared to BDNF Val/Val individuals as reported earlier. Participants . . .

     

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