Association of cortical and subcortical microstructure with disease severity: impact on cognitive decline and language impairments in frontotemporal lobar degeneration

HIGHLIGHTS

  • who: Wencai Ding from the Participants were recruited in the Frontotemporal Lobar Degeneration Neuroimaging Initiative (FTLDNI) database (http://u200b4rtni-u200bftldniu200bini.u200busc.u200bedu), a multisite observational FTLD biomarker study involving , months of longitudinal follow-up with neuropsychological, neuroimaging, CSF, and blood examinations. Participants were enrolled at University of Mayo Clinic, Rochester (MCR), University of California, San Francisco (UCSF), and Massachusetts General Hospital (MGH). Briefly, the inclusion criteria in this research were as follows: participants must meet criteria for bvFTD [3], nfvPPA [4], or svPPA [4] or were age-matched cognitively unimpaired (CU). All participants underwent a thorough neurological . . .

     

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