Association of ifn-γ +874 a/t snp and hypermethylation of the -53 cpg site with tuberculosis susceptibility

HIGHLIGHTS

  • who: Guadalupe Inu00e9s u00c1lvarez from the University of Alabama at Birmingham, United States have published the research work: Association of IFN-u03b3 +874 A/T SNP and hypermethylation of the -53 CpG site with tuberculosis susceptibility, in the Journal: (JOURNAL)
  • what: The aim of this study was to further characterize the genetic and epigenetic mechanisms that regulate IFN-g responses during M. tuberculosis infection. Given the essential role of IFN-g to control mycobacterial replication and development of cellular immune_response (Flesch and Kaufmann, 1987; Serbina et_al, 2001; Salgame, 2005), the case -control study focused on . . .

     

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