Association of the protein-quality-control protein ubiquilin-1 with alzheimer`s disease both in vitro and in vivo

HIGHLIGHTS

  • who: Aleister J. Saunders from the Sichuan University, China have published the research work: Association of the Protein-Quality-Control Protein Ubiquilin-1 With Alzheimer`s Disease Both in vitro and in vivo, in the Journal: (JOURNAL)
  • what: The authors investigated the association of ubiquilin-1 with AD by analyzing the effects of ubiquilin-1 in cell and animal models. The model showed APP and BACE overexpression-related wing veins and altered cell number and tissue compartment size in the Drosophila wing, which can be rescued by ubqn RNAi .
  • how: The authors investigated . . .

     

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