Associations of aspirin and other anti-inflammatory medications with breast cancer risk by the status of cox-2 expression

HIGHLIGHTS

• who: Lusine Yaghjyan from the We requested formalin-fixed paraffin-embedded tissue samples from hospitals throughout the US where women underwent primary breast tumor resectionTumor microarrays (TMAs) were constructed at the Dana Farber Harvard Cancer Center Tissue Microarray Core Facility, Boston, MA. As described previously [21], TMAs were assembled by taking three, .6-mm-diameter cores from each breast cancer sample and inserting cores into a recipient TMA block. Immunohistochemistry for , was conducted on , u03bcm paraffin sections of TMA blocks. Cores with fewer than , cells were excluded from all analyses. For NHS, the staining was first performed . . .
  

   

  

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