Associations of polymorphisms in the peroxisome proliferator-activated receptor gamma coactivator-1 alpha gene with subsequent coronary heart disease: an individual-level meta-analysis

HIGHLIGHTS

• who: PPARGC and collaborators from the Midwestern University, United States have published the paper: Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis, in the Journal: (JOURNAL)
• what: The authors only investigated single SNP associations within a single gene whereas it could be relevant to also address gene-gene interactions and polygenetic scores.
• how: The authors conducted an individuallevel meta-analysis using data from 23 cohort studies within the GENIUS-CHD consortium (Patel et_al 2019a) to investigate the . . .
  

   

  

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