Astragaloside iv alleviates brain injury induced by hypoxia via the calpain-1 signaling pathway

HIGHLIGHTS

• who: Yan Meng and colleagues from the Department of Liaoning Key Laboratory of Cardiovascular and Cerebrovascular Drugs, Jinzhou Medical University, Jinzhou, China have published the paper: Astragaloside IV Alleviates Brain Injury Induced by Hypoxia via the Calpain-1 Signaling Pathway, in the Journal: Neural Plasticity 17 of 14/06/2022
• what: The authors investigated the effect of AS-IV on hypoxia-induced oxidative stress and apoptosis in hippocampal neurons and explored its possible mechanism. This study shows that AS-IV can downregulate the calpain-1/HIF-1u03b1/caspase-3 pathway and inhibit oxidative stress and . . .
  

   

  

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