Astragaloside iv ameliorates isoprenaline-induced cardiac fibrosis in mice via modulating gut microbiota and fecal metabolites

HIGHLIGHTS

• who: Xu-Qin Du and colleagues from the College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of have published the article: Astragaloside IV Ameliorates Isoprenaline-Induced Cardiac Fibrosis in Mice via Modulating Gut Microbiota and Fecal Metabolites, in the Journal: (JOURNAL)
• what: The 16S rRNA sequencing analysis was conducted to determine whether AS-IV treatment affects intestinal microbial community composition. The authors explored the anti-fibrosis effects of AS-IV on ISO-induced mice and discussed the possibility of these effects mediated by intestinal microbiota and fecal metabolites.
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