Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age

HIGHLIGHTS

  • who: William A. Mills from the Brain, Immunology, and Glia Center, University ofStanford, CA, USA have published the research work: Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors demonstrate using focal photothrombosis that astrocyte apoptosis following reperfusion triggers a focal gliovascular plasticity response wherein astrocyte-vascular coverage is maintained. The authors believe that the data points to the rapid plasticity or repair response by neighboring astrocytes as the primary reason that vessel function and BBB . . .

     

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