Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age

HIGHLIGHTS

• who: William A. Mills from the Brain, Immunology, and Glia Center, University ofStanford, CA, USA have published the research: Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors demonstrate using focal photothrombosis that astrocyte apoptosis following reperfusion triggers a focal gliovascular plasticity response wherein astrocyte-vascular coverage is maintained. The authors believe that the data points to the rapid plasticity or repair response by neighboring astrocytes as the primary reason that vessel function and BBB integrity . . .
  

   

  

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