Astrocyte-secreted chordin-like 1 regulates spine density after ischemic injury

HIGHLIGHTS

• who: Elena Blanco-Suarez from the Molecular Neurobiology LaboratoryJefferson University have published the paper: Astrocyte-secreted chordin-like 1 regulates spine density after ischemic injury, in the Journal: Scientific Reports Scientific Reports
• what: The authors investigated the contribution of the astrocyte-enriched synapse-regulating protein Chrdl1 to the response to PT injury. This suggests that the upregulation of Chrdl1 is context-specific to CNS acute injury, and that the functional role of Chrdl1 that the authors show here is limited to these settings. The work shows that increased expression of Chrdl1 can be a detrimental . . .
  

   

  

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