Astrocytes underlie a faster-onset antidepressant effect of hypidone hydrochloride (yl-0919)

HIGHLIGHTS

• who: March and colleagues from the Minzu of China have published the paper: Astrocytes underlie a faster-onset antidepressant effect of hypidone hydrochloride (YL-0919), in the Journal: (JOURNAL)
• what: The authors first validated the faster antidepressant activity of YL-0919 compared to fluoxetine, which usually shows effects after 3-5 weeks in a chronic stress depression model.
• how: After 14 days of treatment the mice were tested for behavior in the order from less to more stressful tests as indicated in Figure 1A with a 24 h interval between tests to permit . . .
  

   

  

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