Asymmetric 1,4-functionalization of 1,3-enynes via dual photoredox and chromium catalysis

HIGHLIGHTS

  • who: Feng-Hua Zhang from the (UNIVERSITY) have published the research work: Asymmetric 1,4-functionalization of 1,3-enynes via dual photoredox and chromium catalysis, in the Journal: (JOURNAL)
  • how: These results indicated that the reaction was sensitive to moisture and air probably due to the involvement of unstable alkyl chromium complexes.

SUMMARY

    This method features readily available starting materials, broad substrate scope, good functional_group compatibility, high regioselectivity, and simultaneous control of axial and central chiralities. The radical 1,4-functionalization of 1,3-enynes via allenyl or propargylic radicals . . .

     

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