Asymmetric 1,4-michael addition reaction of azadienes with -thiocyanoindanones catalyzed by bifunctional chiral squaramide

HIGHLIGHTS

• who: Xiao-Yan Dong and Da-Ming Du from the School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China have published the research work: Asymmetric 1,4-Michael Addition Reaction of Azadienes with -Thiocyanoindanones Catalyzed by Bifunctional Chiral Squaramide, in the Journal: Molecules 2021, 26, 5146. of 25/08/2021
• what: In this paper the organocatalytic 1 reaction of azadienes and α-thiocyanoindanones was investigated.
• how: Compared with entry 28 the results showed that the yield enantioselectivity and diastereoselectivity decreased . The best result was obtained using 0.05 mmol 1a 0 . . .
  

   

  

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