Asymmetric bmp4 signalling improves the realism of kidney organoids

HIGHLIGHTS

  • who: Christopher G. Mills from the Deanery of Biomedical Science, University of Edinburgh, Edinburgh, XB, UK Centre for Cardiovascular have published the research work: Asymmetric BMP4 signalling improves the realism of kidney organoids, in the Journal: Scientific Reports Scientific Reports of 26/06/2017
  • what: The authors show that application of BMP4releasing beads in one place in an organoid can break the symmetry of the system causing a nearby collecting duct to develop into a uroplakin-positive broad unbranched ureter-like u2018trunk` from one end of which true collecting duct branches radiate and induce nephron . . .

     

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