Asymmetric total synthesis of all rugulovasine stereoisomers and preliminary evaluation of their biological properties

HIGHLIGHTS

• who: Very Important Paper from the (UNIVERSITY) have published the research: Asymmetric Total Synthesis of All Rugulovasine Stereoisomers and Preliminary Evaluation of Their Biological Properties, in the Journal: (JOURNAL)
• what: Now, the authors report the realization of this strategy for the total synthesis of all four stereoisomers of rugulovasine and their preliminary biological evaluation on several key central nervous system (CNS) receptors. The aim of the second -generation functional assays was to determine the effective half-maximal inhibitory concentrations (IC50) for all stereoisomers of rugulovasine on the human 5-HT1A receptor, which is the most . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.