Atf1/mir-214-5p/itga7 axis promotes osteoclastogenesis to alter ovx-induced bone absorption

HIGHLIGHTS

• who: Lu-Lin Liu from the All animal experiments were approved by the Institutional Animal Care and Use Committee of Soochow University3-month-old C BL/, female mice were designated to , groups: ovariectomized group (OVX, n=6), sham group (Sham, n=6), OVX + antagomir NC (n=6) and OVX + miR-214-5p antagomir (n=6). OVX group was subjected to bilateral ovariectomy , days after acclimatization, while intact ovaries were retained in sham group. To prevent infection, each mouse was injected penicillin within the , days after operation. , u03bcl antagomir NC and miR-214-5p antagomir were given through . . .
  

   

  

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