Atherosclerosis: from molecular biology to therapeutic perspective 2.0

HIGHLIGHTS

  • who: Ida Perrotta from the DepartmentUniversity of have published the article: Atherosclerosis: From Molecular Biology to Therapeutic Perspective 2.0, in the Journal: (JOURNAL) of 11/Nov/2022

SUMMARY

    Copyright: Atherosclerosis is a chronic inflammatory disease of large- and medium-sized arteries involving aberrant immune-inflammatory responses, dysfunctional molecular pathways, and impaired tissue repair mechanisms. Atherosclerosis begins with endothelial damage, proceeds with the subendothelial retention of modified low-density lipoproteins (LDL) and the phenotypic switching of the smooth muscle cells (SMCs), and culminates with plaque instability and eventually with plaque rupture with its . . .

     

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