Atorvastatin attenuates ferroptosis-dependent myocardial injury and in ammation following coronary via the hif1a/ ptgs2 pathway

HIGHLIGHTS

  • who: . and collaborators from the Qatar University, Qatar University of Duisburg-Essen, Germany have published the Article: Atorvastatin attenuates ferroptosis-dependent myocardial injury and in ammation following coronary via the Hif1a/ Ptgs2 pathway, in the Journal: (JOURNAL)
  • what: ATV reduced the levels of TNF-u03b1 and IL-1u03b2 induced by Ptgs2 silencing ameliorated ferroptosismediated myocardial injury and inflammation following CME To further investigate the regulatory mechanism of ferroptosis and inflammation following CME, the authors focused on the function of Ptgs2, a core factor of ferroptosis, in CME-induced myocardial injury. The authors demonstrated that ATV . . .

     

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