Atp-citrate lyase promotes axonal transport across species

HIGHLIGHTS

  • who: Aviel Even from the Shmunis School Aviv University Neurosciences, Grenoble, France, Inserm, , Grenoble, France. have published the paper: ATP-citrate lyase promotes axonal transport across species, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 18/Dec/1986
  • what: By combining cellular and molecular analyses in mouse cortical neurons in_vitro and fly larva motoneurons (MNs) in_vivo, the authors show that Elongator is expressed in vesicles and modulates axonal transport and acetylation of α-tubulin across species by regulating the stability of ATP-citrate lyase (Acly). The authors show that loss of Elongator activity does not worsen . . .

     

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