Atp13a2 gene silencing in drosophila affects autophagic degradation of a53t mutant -synuclein

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  • who: Nisha R. Dhanushkodi and collaborators from the Department of Biochemistry and Molecular Biology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain POBox, United Arab Emirates have published the research work: ATP13A2 Gene Silencing in Drosophila Affects Autophagic Degradation of A53T Mutant -Synuclein, in the Journal: (JOURNAL)
  • what: The authors examined the effect of ATP13A2 knockdown on the expression, aggregation, and neurotoxicity of wild-type (WT) u03b1-syn, and A30P- and A53T-u03b1-syn mutants in a Drosophila model. This study showed that mutant A53T-u03b1-syn forms more triton insoluble . . .

     

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