Atr is essential for preservation of cell mechanics and nuclear integrity during interstitial migration

HIGHLIGHTS

  • who: Gururaj Rao Kidiyoor from the Institut, Paris, France, University have published the paper: ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 25/08/2020
  • what: The authors explore the possibility that ATR-mediated mechanical communication are also important for the state of the NE itself and, having obtained evidence to this effect, explore its functional implications. The authors show that ATR is essential for neurogenesis and cancer cell migration, two processes in which cells and their nuclei must squeeze through . . .

     

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