Atroposelective amination of indoles via chiral center induced chiral axis formation

HIGHLIGHTS

  • who: Yong Wang and colleagues from the Key Laboratory of Natural Medicines, Department of Organic Chemistry, China Pharmaceutical University have published the article: Atroposelective Amination of Indoles via Chiral Center Induced Chiral Axis Formation, in the Journal: Molecules 2022, 9008 of /2022/
  • what: This work provides a novel method for this purpose via amination of amino acid derivatives at the C2 position of the indole and center induced

SUMMARY

    Atropisomers around the C-N chiral axis, which have a typical chiral axis connecting a substituted nitrogen and the aryl-related hindrance . . .

     

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