Attenuation of hect-e3 ligase expression rescued memory deficits in 3xtg-ad mice

HIGHLIGHTS

• who: Ingrid Y. Liu from the Affairs, United States have published the research work: Attenuation of HECT-E3 ligase expression rescued memory deficits in 3xTg-AD mice, in the Journal: (JOURNAL)
• what: The M01 dissolves better in DMSO; and therefore, the authors design a DMSO only group (the vehicle group) to evaluate the possible effect of DMSO on the study . The authors demonstrate that reducing the excessive inflammatory response by modulating HECT-E3 ligase to enhance the autophagy process is a promising therapeutic approach to preventing early memory decline in AD.
• how: On . . .
  

   

  

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