Atxn2-mediated pi3k/akt activation confers gastric cancer chemoresistance and attenuates cd8 t cell cytotoxicity

HIGHLIGHTS

  • who: Qi Wang and colleagues from the Honghui Hospital, Xi`an Jiaotong University, Xi`an, Shaanxi, China have published the article: ATXN2-Mediated PI3K/AKT Activation Confers Gastric Cancer Chemoresistance and Attenuates CD8 T Cell Cytotoxicity, in the Journal: Journal of Immunology Research of 24/06/2022
  • what: The authors show that ATXN2 is strongly expressed in GC and induces chemoresistance by activating the PI3K/ AKT signalling pathway. The study provides new ideas and strategies for clinical chemoresistance and immunotherapy resistance.

SUMMARY

    Gastric cancer (GC), the cells of which compose one . . .

     

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