HIGHLIGHTS
- who: Jasmine M. Manouchehri from the Comprehensive Center, The Ohio State University, Columbus, OH, United States have published the Article: Augmentation of Extracellular ATP Synergizes With Chemotherapy in Triple Negative Breast Cancer, in the Journal: (JOURNAL) of 14/01/2022
- what: The authors aimed to identify clinically approved compounds that modulate eATP levels.
- how: The authors showed that consistent with this activity ivermectin sensitized TNBC cell lines to chemotherapy.
SUMMARY
Given that eATP is toxic to cancer cells, the authors hypothesized that augmenting the release of eATP through P2RX . . .
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