Aurora b kinase inhibition by azd1152 concomitant with tumor treating fields is effective in the treatment of cultures from primary and recurrent glioblastomas

HIGHLIGHTS

  • who: Dietmar Krex and collaborators from the Department of Neurosurgery, University Hospital, Technical University Dresden, Dresden, Germany have published the research work: Aurora B Kinase Inhibition by AZD1152 Concomitant with Tumor Treating Fields Is Effective in the Treatment of Cultures from Primary and Recurrent Glioblastomas, in the Journal: (JOURNAL)
  • what: The authors investigate whether the combination of TTFields with the chemical Aurora B kinase inhibitor AZD1152 enhances the anti-tumor effect on glioblastoma cells by additionally inhibiting cytokinesis.
  • how: Sequencing data were compared with sequence of wild-type p53 using ApE-A Plasmid . . .

     

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