Autologous humanized mouse models to study combination and single-agent immunotherapy for colorectal cancer patient-derived xenografts

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  • who: Preeti Kanikarla Marie and colleagues from the The State University of New Jersey, United States have published the article: Autologous humanized mouse models to study combination and single-agent immunotherapy for colorectal cancer patient-derived xenografts, in the Journal: (JOURNAL)
  • what: The analysis shows how the total cell percentage was distributed within the intratumoral (Supplemental Figures 4C-F) stromal (Supplemental Figures 4I-L) and tumor compartments. As in other transplant models, onset of GVHD in the model the authors used in this study has been attributed to the expansion of human T_cells that are . . .

     

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