HIGHLIGHTS
- who: Osteoarthritis (OA and colleagues from the Clinical College, Ningxia Medical University, Yinchuan, China have published the research: Autophagy attenuates in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling, in the Journal: (JOURNAL)
- what: Although NLRP3 has a potential role in a variety of chronic inflammatory diseases, the authors focused on OA. In this study, OA was induced in C57BL/6 mice using DMM, and the effect of autophagy on pyroptosis of OA chondrocytes and subchondral bone remodeling was investigated. The study showed that the expression levels of NLRP3 in chondrocytes were significantly . . .
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