HIGHLIGHTS
- who: Shruti Singla from the University of have published the research work: Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 11/07/2019
- what: The authors examine the fate of aneuploid cells during implantation and early post-implantation development when the cells of the embryonic lineage initiate for the first time extensive proliferation and reorganisation in shape, gene_expression, epigenetic signatures and metabolism, laying down the foundation of the developing body. Together, the findings suggest that the p53 pathway induces autophagy-mediated elimination . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.