Autophagy/mitophagy regulated by ubiquitination: a promising pathway in cancer therapeutics

HIGHLIGHTS

  • who: Seung-Cheol Jee and Heesun Cheong from the Division of Cancer Biology, Research Institute, National Cancer Center, Goyang-si, Republic of Korea have published the research: Autophagy/Mitophagy Regulated by Ubiquitination: A Promising Pathway in Cancer Therapeutics, in the Journal: Cancers 2023, 15, 1112. of /2023/

SUMMARY

    The ubiquitin-proteasome system (UPS) and autophagy are important for the maintenance of cellular homeostasis. Recent reports have suggested that UPS is interconnected with autophagy, and many studies have focused on the relationship between autophagy and the ubiquitination process. One predominant hypothesis is that UPS . . .

     

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