Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation

HIGHLIGHTS

  • who: Natalia Reglero-Real from the Centre University of London, London EC M BQ, UK have published the research work: Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation, in the Journal: (JOURNAL) of September/14,/2021
  • what: Because the authors showed that neutrophil trafficking in Atg5DEC mice is PECAM-1 dependent , the authors focused on this molecule under conditions of autophagy deficiency as an illustration of endothelial leukocyte-trafficking machinery.
  • how: Next the authors explored the prevalence of this reaction during the course of an acute inflammatory model of ischemiareperfusion injury . . .

     

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