Autophagy role(s) in response to oncogenes and dna replication stress

HIGHLIGHTS

  • who: Riccardo Vanzo from the Danish Cancer Society Research Center, Copenhagen, Denmark have published the research work: Autophagy role(s) in response to oncogenes and DNA replication stress, in the Journal: (JOURNAL)
  • what: Somewhat unexpectedly, the data show that mitochondria in both ATG5- and ATG7-depleted cells are operational, featuring Autophagy and recovery from replication stress Looking for additional evidence to explain how autophagy is related to RS, the authors focused the attention on the regulation of nucleotide levels. The authors show that prolonged treatments with RS-inducing drugs lead to increased autophagy observed also . . .

     

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