Autophagy suppresses the pathogenic immune response to dietary antigens in cystic fibrosis

HIGHLIGHTS

• who: Valeria R. Villella from the CF mice homozygous for the, del-CFTR in the FVB/, outbred background (Cftrtm EUR, del, FVB/129, abbreviated CftrF508del/F508del) were obtained from Bob Scholte, Erasmus Medical CenterRotterdam, The Netherlands, CF coordinated action program EU FP LSHMCT-2005-01893250. Transgenic KO Cftr mice (B6., KOCftrtm UNC, abbreviated Cftr-/-), were purchased from The Jackson Laboratory (Bar Harbor, ME, USA). The heterozygous CftrF508del/+ males were backcrossed with heterozygous Cftr+/- females to obtain, del/null CFTR heterozygous mice (abbreviated CftrF508del/-). Female CftrF508del/+ mice were backcrossed to the C BL/ J background Becn1+/- male mice . . .
  

   

  

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