Autoreactive lymphocytes in multiple sclerosis: pathogenesis and treatment target

HIGHLIGHTS

  • who: Rongzeng Liu from the Ramou0301n y Cajal University Hospital, Spain have published the Article: Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target, in the Journal: (JOURNAL)
  • what: This review summarizes the latest advances in the understanding of the autoreactive lymphocyte populations that are identified as playing role in the pathogenesis of MS. This study demonstrated that the hypomethylation of this MS susceptibility gene locus can induce the high expression of HLA-DRB1, found in these patients . The research now focused on the identification of immune-modulating agents and monoclonal_antibodies, with the ability to . . .

     

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