HIGHLIGHTS
- who: Oscar P. Kuipers from the (UNIVERSITY) have published the research: Autoregulation of Nisin Biosynthesis in Lactococcus lactis by Signal Transduction (*), in the Journal: (JOURNAL)
- what: A model based on previous work and on this study shows the possible sequence of events with regard to nisin biosynthesis and regulation (Fig 4).
SUMMARY
The post-translationally modified, antimicrobial peptide nisin is secreted by strains of Lactococcus lactis that contain the chromosomally located nisin biosynthetic gene cluster nisABTCIPRKFEG. Transcription of the DnisA gene is restored by adding subinhibitory amounts of nisin, nisin mutants . . .
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