Autotaxin has a negative role in systemic inflammation

HIGHLIGHTS

• who: Ioanna Nikitopoulou et al. from the National and Kapodistrian University of Athens Medical School, Evangelismos Hospital have published the paper: Autotaxin Has a Negative Role in Systemic Inflammation, in the Journal: (JOURNAL)
• what: In this the authors aimed toProtects assess Mice the role ATX in systemic 2.1. In present the present study, the authors genetically identified the ATX-LPA in LPSendotoxemia in mice.inMore the authors demonstrated that haploinsufficient ATXdf/+ induced endotoxemia mice.specifically, More specifically, the authors demonstrated that haploinsufficient df/+producing mice, 50% reduced serumserum ATX levels . This study showed that . . .
  

   

  

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