Avidity in antibody effector functions and biotherapeutic drug design

HIGHLIGHTS

  • who: Simone C. Oostindie from the Genmab, Utrecht, Netherlands, Department of Immunology, Leiden University Medical Center, Leiden, Netherlands. , Department of Antibody Engineering, Genentech, San Francisco, CA, USA. , Sparring Bioconsult, Odijk, Netherlands. , Lava Therapeutics, Utrecht, Netherlands. have published the Article: Avidity in antibody effector functions and biotherapeutic drug design, in the Journal: (JOURNAL)
  • what: The authors describe how affinity and avidity tuning of engineered antibody formats are enabling a new wave of differentiated antibody drugs with tailored properties and novel functions, promising improved treatment options for a wide variety of diseases. This study investigates the pathways . . .

     

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